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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Dev Biol. 2008 Oct 31;325(1):211–224. doi: 10.1016/j.ydbio.2008.10.025

Figure 4. Model for results expected when PCs expand out of the neck (progenitor) zone and into the base (differentiated) cell zone.

Figure 4

It has been assumed that PCs establish a chemical gradient or work by cell-cell contact to control terminal differentiation of the zymogenic lineage (left). If PCs were to be extended into the base zone (right), zymogenic lineage cells would be unable to escape this gradient and would fail to differentiate.