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. Author manuscript; available in PMC: 2009 Feb 2.
Published in final edited form as: Magn Reson Med. 2007 Feb;57(2):437–441. doi: 10.1002/mrm.21143

FIG. 1.

FIG. 1

a: SIR with an FSE readout. Each acquisition is made through a different line of k-space. td is the delay from the last 180° pulse until the next repetition. Multiple images are acquired and fit to a biexponential function of ti. b: The simulated evolution of the normalized z-magnetization of the free (dashed) and macromolecular (solid) proton pools. Note the roughly exponential decay of Mm(t)/Mm∞ during the FSE evolution with a time constant of 1/kmf. After the RF pulse train, both proton pools recover together with the longer time constant 1/R1–. The parameter values used for the simulation were R1f = 1 Hz, R2f = 25 Hz, R1m = 1 Hz, R2m = 100 kHz, kfm = 3 Hz, kmf = 30 Hz, pulse width = 1.5 ms, ti= 50 ms, echo spacing = 10 ms, and eight echoes. The blips of Mf(t)/Mf∞ during the FSE evolution are due to the rotation during the RF pulses and are not important for our results.