Table 2.

Serum antibody (IgG) levels of mice treated with decreasing dose of once weekly PEG-Av-p.C503S/p.C565S-PAL

Day	Antibody (IgG) titer, dilution factor; median/range
	Vehicle	4 I.U., weeks 1–10; 2 I.U., weeks 11–16	4 I.U., weeks 1–10; 1 I.U., weeks 11–16	2 I.U., weeks 1–10; 1 I.U., weeks 11–16
0	50/50–50	50/50–50	50/50–50	50/50–50
12	50/50–50	50/50–150	50/50–150	50/50–50
19	50/50–50	50/50–150	50/50–150	50/50–50
26	50/50–50	50/50–150	50/50–450	50/50–150
33	50/50–50	50/50–450	150/50–450	50/50–150
40	50/50–50	50/50–1,350	50/50–1,350	50/50–150
61	50/50–50	450/50–1,350	450/50–1,350	300/50–1,350
75	50/50–50	150/50–450	450/50–1,350	450/50–450
89	50/50–50	150/150–1,350	450/50–1,350	150/50–150
103	50/50–50	450/150–1,350	450/150–12,150	450/50–450
113	50/50–50	450/50–4,050	450/150–4,050	450/150–4,050
120	50/50–50	150/50–450	150/50–1,350	150/50–450

n = 16.