Figure 6.

Variability in PI3K and 3′ PI phosphatase expression results in broadening of the fibroblast density and PDGF concentration profiles. Sampling model II, with lognormal distribution and σ = 0.25, was used. (A) spatial profiles of PDGF concentration and fibroblast density. Individual cell parameters were varied as follows: r_max only (dotted curves), r_max and e_max (dashed curves), or r_max, e_max and p_max (solid curves). (B) spatial profile of mean p_max value, with variation of p_max only (dashed curve) or all three of r_max, e_max and p_max (solid curve).