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. Author manuscript; available in PMC: 2009 Feb 3.
Published in final edited form as: ACS Chem Biol. 2007 May 4;2(5):315–319. doi: 10.1021/cb700036x

Figure 1. Ligand structures and synthesis.

Figure 1

a) Structures of a generic AHL, OHHL (1) (the natural autoinducer ligand of V. fischeri), and selected known synthetic inhibitors of LuxR or other R protein function (2–5). b) Solid-phase synthetic route to PHL library 11. DIC = N,N′-diisopropyl-carbodiimide. HOBt = N-hydroxybenzotriazole. µW = temperature-controlled microwave irradiation.

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