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Inhibition of Caco2 cell adhesion to CD11b/CD18 by reduction of CD44v3 via CD44v3 siRNA and by anti-CD44v3 antibody. A and B, reduction of CD44v3 in Caco2 cells transfected with CD44v3 siRNA shown by Western blot analysis and flow cytometry, respectively. MFI, mean fluorescence intensity. C, adhesion of Caco2 cells to immobilized CD11b/CD18. Antibodies were used at 25 μg/ml. The data are presented as the means ± S.D. (n = 3).
