Table1.
Follow-up characteristics of subjects
| Normoalbuminuria (AER <30 mg/day) | Microalbuminuria (AER = 30–299 mg/day) | Macroalbuminuria (AER ≥300 mg/day) | |
|---|---|---|---|
| n | 1,056 | 80 | 24 |
| Intensive/standard treatment | 554/502 | 31/49* | 6/18* |
| M/F | 580/476 | 51/29 | 18/6 |
| 1°/2° | 570/486 | 18/62† | 2/22† |
| Age (years) | 33.6 (33.2–34.0) | 32.8 (31.1–34.6) | 33.0 (30.3–35.6) |
| BMI (kg/m2) | 25.8 (25.6–26.1) | 25.5 (24.7–26.2) | 24.6 (23.4–25.7) |
| AER (mg/day) | 10.0 (9.7–10.4) | 93.6 (78–109)† | 1,931 (1,099–2,764)† |
| CCr (ml/s · 1.73 m−2) | 2.02 (1.98–2.05) | 2.09 (1.98–2.20) | 1.72 (1.45–1.98)*‡ |
| HbA1c (%) | 8.01 (7.90–8.12) | 8.66 (8.12–9.21)* | 8.93 (7.96–9.90)† |
| Serum creatinine (µmol/l) | 76.3 (75.5–77.0) | 77.6 (75.0–80.1) | 107.2 (89.5–124.9)†§ |
| Systolic blood pressure (mm Hg) | 115 (114–116) | 122 (119–125)† | 131 (127–135)†‡ |
| Diastolic blood pressure (mm Hg) | 73.6 (73.1–74.2) | 78.2 (76.6–79.8)† | 84.5 (80.7–88.3)†‡ |
| Triglyceride (mmol/l) | 0.91 (0.88–0.94) | 1.11 (0.98–1.25)* | 1.65 (1.27–2.03)† |
| Total cholesterol (mmol/l) | 4.63 (4.58–4.68) | 4.76 (4.55–4.97) | 5.54 (4.99–6.09)† |
| LDL cholesterol (mmol/l) | 2.89 (2.84–2.93) | 3.01 (2.84–3.18) | 3.64 (3.18–4.09)† |
| HDL cholesterol (mmol/l) | 1.33 (1.31–1.34) | 1.25 (1.18–1.31) | 1.15 (1.05–1.25) |
| ApoAI (mg/dl) | 138 (137–139) | 138 (133–143) | 140 (133–147) |
| ApoB (mg/dl) | 83 (82–84) | 89 (84–94) | 110 (99–121) |
| Lp(a) (mg/dl) | 21 (19–22) | 20.8 (16.1–25.6) | 20.9 (9.0–32.9) |
Data are means (95% CI).
*
P = 0.05 for comparison with the normoalbuminuric value
†
P = 0.01 for comparison with the normoalbuminuric value
‡
P = 0.05 for comparison with the microalbuminuric value
§
P = 0.01 for comparison with the microalbuminuric value.