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. Author manuscript; available in PMC: 2009 Oct 3.
Published in final edited form as: J Org Chem. 2008 Aug 30;73(19):7481–7485. doi: 10.1021/jo801269m

Table 5.

Cross-Coupling of Potassium Cyclobutyltrifluoroborate with Various Aryl- and Heteroaryl Chloridesa

graphic file with name nihms86313f6.jpg
entry chloride product % isolated yield
1 graphic file with name nihms86313t33.jpg
6a
graphic file with name nihms86313t34.jpg
7a
82
2 graphic file with name nihms86313t35.jpg
6b
graphic file with name nihms86313t36.jpg
7b
74
3 graphic file with name nihms86313t37.jpg
6c
graphic file with name nihms86313t38.jpg
7c
45
4 graphic file with name nihms86313t39.jpg
6d
graphic file with name nihms86313t40.jpg
7d
63
a

All reactions used 0.5 mmol of the aryl- or heteroaryl chloride and 0.505 mmol of potassium cyclobutyltrifluoroborate.