Table 7.
Distribution of the 580 SNP (307 silent and 273 missense) between the extracellular (EC), transmembrane (TM) and intracellular (IC) domains.
| Domain name | Number of missense SNP with AA group change | Number of missense SNP without AA group change | Total number of missense SNP | Total number of silent SNP |
| EC1 | 12 | 7 | 19 | 20 |
| TM1 | 7 | 17 | 24 | 21 |
| IC1 | 8 | 3 | 11 | 8 |
| TM2 | 7 | 8 | 15 | 27 |
| EC2 | 5 | 8 | 13 | 17 |
| TM3 | 4 | 5 | 9 | 7 |
| IC2 | 9 | 5 | 14 | 15 |
| TM4 | 7 | 16 | 23 | 20 |
| EC3 | 13 | 12 | 25 | 45 |
| TM5 | 12 | 6 | 18 | 21 |
| IC3 | 20 | 11 | 31 | 16 |
| TM6 | 5 | 15 | 20 | 35 |
| EC4 | 5 | 9 | 14 | 13 |
| TM7 | 4 | 12 | 16 | 22 |
| IC4 | 12 | 9 | 21 | 20 |
| Total | 130 | 143 | 273 | 307 |