Fig. 2A–D.

Micrographs of neighboring samples stained with (A) β-catenin, (B) α-SMA, and (C) a positive control with vimentin in Patient 1-1 show a staining zone of involution (white arrow) surrounded by tissue in the proliferative zone with only vimentin staining fibroblasts and vascular infiltration (positive endothelial staining for α-SMA, black arrow) (original magnification, ×400). A magnification (×1000) of the selected staining area (D = square in micrograph A) with β-catenin staining shows nuclear and cytoplasmic accumulation in the myofibroblasts in contrast to the neighboring nonstaining fibroblasts.