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. Author manuscript; available in PMC: 2010 Feb 4.
Published in final edited form as: J Am Chem Soc. 2009 Feb 4;131(4):1344–1345. doi: 10.1021/ja807705z

Figure 1.

Figure 1

Molecular modeling showing the accommodation of a 1′-cyano substituent on pseudo-2′-deoxyuridine containing DNA co-crystallized with human UDG (PDB ID: 1EMH). The arrow points towards the cyano substituent.