TABLE 7.
Effect of diet on bacterial burden in the lung and spleen of M. tuberculosis-infected guinea pigs fed (n-3) or (n-6) fatty acid diets for 3 and 6 wk 1
| 3 Wk postinfection
|
6 Wk postinfection
|
||||||
|---|---|---|---|---|---|---|---|
| Lung2 | Spleen | Lung | Spleen | ||||
| log 10 cfu | |||||||
| (n-3) PUFA | 5.73 ± 0.11* | 4.36 ± 0.29 | 5.7 ± 0.25** | 6.07 ± 0.21 | |||
| (n-6) PUFA | 5.19 ± 0.15 | 3.77 ± 0.26 | 4.4 ± 0.16 | 5.97 ± 0.19 | |||
1
Values are group means ± SEM, n = 5. Asterisks indicate different from (n-6) PUFA, *P = 0.01, **P = 0.001.
2
Minimum detection limit of log10 cfu is 2.35 for the lung and 1.35 for the spleen.