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. Author manuscript; available in PMC: 2009 Feb 3.
Published in final edited form as: Oncogene. 2008 Oct 20;28(2):157–169. doi: 10.1038/onc.2008.380

Figure 4. Silencing of CDC37 reduces cell proliferation.

Figure 4

Proliferation of (a) HCT116 or (b) HT29 human colon cancer cells measured by SRB assay following no transfection, mock or siRNA transfection. Transfections were repeated at day 4 to sustain the silencing of CDC37. Mean from at least 3 independent repeats ± SE, *p<0.05 by paired students t-test in comparison with each control. (c) Representative cell cycle profile in HCT116 cells at 5 days following siRNA or mock transfection. (d) Mean cell cycle distribution of HCT116 cells at 5 days from 3 independent repeats ± SE, *p<0.05, **p<0.01 by non-paired students t-test in comparison with mock and IC4 controls.