(a) Time course of HSP72, CRAF, phosphorylated AKT, AKT and CDK4 expression following 48h siRNA or mock transfection and 17-AAG treatment at 5XGI50 in HCT116 human colon cancer cells. (d) Time course of HSP72, GR, ERBB2, CRAF, phosphorylated AKT, AKT, phosphorylated ERK1/2, ERK2 and CDK4 expression following siRNA or mock transfection for 72h and 115nM 17-AAG treatment in HCT116 human colon cancer cells.