Table 1.

Brain responses to self-controlled and externally controlled pain (main effect of pain; p < 0.001 uncorrected)

Brain region	Laterality	Brodmann area	MNI coordinates			Cluster size (voxel)	Z score
			x	y	z
Insula/operculum/temporal lobe	R	48	57	0	3	871	4.98
	R	48	45	6	−9		4.88
	R	48	54	18	9		4.75
	L	48	−39	−18	15	18	4.27
	L	48	−42	3	−9	183	4.10
	L	38	−54	6	−6		4.02
	L	48	−57	−3	6		4.01
	L	48	−36	0	9	4	3.90
	L	48	−54	−18	12	9	3.82
Pallidum	L		−15	6	0	48	4.55
	R		15	6	−3	2	3.21
Caudate nucleus	L		−15	18	6		3.43
	R		12	9	15	10	3.45
	R		12	12	3		3.23
SII	L	48	−51	−24	27	13	3.96
	L	48	−63	−27	21		3.34
	R	48	51	−45	33	7	3.38
OFC	R	47	51	42	−9	6	3.86
	R	11	24	30	−15	15	3.77
	L	11	−24	39	−9	12	3.82
	L	11	−21	21	−6	3	3.61
Inferior parietal lobe/SII	L	40	−57	−42	36	45	3.85
	L	40	−57	−42	45		3.49
	L	48	−48	−42	24		3.47
ACC	R/L	25	0	31	2	6	3.77

L, Left; R, right; SII, secondary somatosensory cortex. p < 0.001 uncorrected at voxel level; voxel size, 2 × 2 × 2 mm.