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Effect of the prolyl oligopeptidase inhibitor BCPP on metabolism of [3H]tasidotin by CCRF-CEM leukemia cells. Cells were incubated for 18 h with 20 μM [3H]tasidotin without (A) or with (B) 12.5 μM BCPP, and soluble radiolabel was evaluated by HPLC and flow detector analysis.
