Table 1.
Modulation of hepatic unidentified polar DNA adducts by diets supplemented with berries (5%w/w) or ellagic acid (400 ppm) in female CD-1 mice.
| Adduct subgroup | P-1 | P-2 | PL-1 | L-1 | Total |
|---|---|---|---|---|---|
| Adducts/ 109 nucleotides (mean ± SE) | |||||
| Control(n=4) | 4810 ± 596 | 3398 ± 316 | 197 ± 32 | 3074 ± 697 | 11,479 ± 1128 |
| Strawberry(n=4) | 3726 ± 1053 | 2182 ± 647 | 187 ± 23 | 2404 ± 502 | 8452 ± 1561 |
| Blueberry(n=5) | 4982 ± 513 | 2243 ± 285 | 186 ± 37 | 1870 ± 248 | 8833 ± 668 |
| Red raspberry(n=5) | 1803 ± 239 * | 1090 ± 149 ** | 84 ± 16 | 1790 ± 433 | 4733 ± 333** |
| p value | p < 0.05 | p < 0.001 | NS | NS | p < 0.001 |
| Ellagic acid(n=5) | 2060 ± 306 * | 1207 ± 106 * | 101 ± 8 | 2540 ± 254 | 5908 ± 540 * |
| p value | p < 0.05 | p < 0.01 | NS | NS | p < 0.01 |