. Author manuscript; available in PMC: 2009 Feb 4.

Published in final edited form as: Neurogenetics. 2008 Mar 14;9(2):127–138. doi: 10.1007/s10048-008-0122-8

Table 1.

Demographic and clinical characteristics of the participants in the three independent datasets.

Characteristic	Family Dataset		Case-Control Dataset
Characteristic	North European	Caribbean Hispanic	NE Cases	NE Controls
Total number of AD families	124	209	N/A	N/A
Total Number of Subjects	685	1,147	183	224
Number Patients with AD	321	589	N/A	N/A
Number At-risk Relatives	342	499	N/A	N/A
Number Nuclear sibships (>2 siblings genotyped)*	163	272	N/A	N/A
Number Patients per family, mean (range)	2.6 (1-6)	2.85(1-12)	N/A	N/A
Number At-risk persons per family, mean (range)	2.8 (0-18)	2.41(0-15)	N/A	N/A
Mean age at onset (years)	70 ± 9	73±11	76±7	73±8
Autopsy Confirmation (one per family)	58 (50%)	5 (2.2%)	0 (0%)	0 (0%)