Table 4.
Results of single point association analysis combining family and case-control data. For estimation of empirical p-value, we estimated empirical p-value based on 10,000 replicates.
| SNP # | SNP | Obs | Exp | Chi-sq | P | Pointwise Empirical P |
Studywise Empirical P |
|---|---|---|---|---|---|---|---|
| 1 | rs2532501 | 171 | 155.2 | 6.739 | 0.009434 | 0.0109 | 0.0649 |
| 2 | rs2532500 | 177 | 159.2 | 8.54 | 0.00347 | 0.0064 | 0.0259 |
| 3 | rs2008134 | 103 | 106.2 | 0.3203 | 0.5714 | 0.6123 | 0.9954 |
| 4 | rs2072373 | 57 | 64.78 | 2.711 | 0.09968 | 0.1093 | 0.4803 |
| 5 | rs7311174 | 99 | 98.95 | 8.68E-05 | 0.9926 | 0.9800 | 1.0000 |
| 6 | rs2072374 | 98 | 98.35 | 0.003902 | 0.9502 | 0.9620 | 1.0000 |
| 7 | rs740850 | 187 | 165.3 | 11.84 | 0.00058 | 0.0004 | 0.0048 |
| 8 | rs3741916 | 76 | 87.93 | 5.293 | 0.02141 | 0.0177 | 0.1361 |
| 9 | rs3741918 | 62 | 70.32 | 3.028 | 0.08183 | 0.0758 | 0.4076 |
| 10 | rs1060620 | 92 | 95.93 | 0.5488 | 0.4588 | 0.4650 | 0.9810 |
| 11 | rs1060619 | 89 | 92.26 | 0.3965 | 0.5289 | 0.5396 | 0.9937 |
| 12 | rs740852 | 30 | 28.44 | 0.2185 | 0.6402 | 0.6549 | 0.9988 |