Table 1.

The ten-fold-cross-validated accuracy for predicting the ϕ and ψ angles, and RSA from five experiments. Standard deviations between ten folds are also shown for Experiments III, IV and V

Experiment	I (500,1,21)a		II (500,2,21)a		III (2479,1,21)a		IV (2479,2,21)a		V (2479,2,41)a
Guided?	Nob	Yesc	No	Yes	No	Yes	No	Yes	No	Yes
ψ-Q10d	43.5%	45.3%	48.1%	49.5%	47.0 ± 0.8 %	48.4 ± 0.5 %	49.8 ± 0.5%	50.7 ± 0.5%	48.5 ± 0.4%	50.1 ± 0.6%
ψ-Q10%e	61.1%	63.0%	65.6%	66.8%	64.6 ± 0.7 %	65.8 ± 0.5 %	67.3 ± 0.4%	68.5 ± 0.5%	65.7 ± 0.4%	67.8 ± 0.6%
ψ-PCCf	0.72	0.729	0.757	0.770	0.741 ± 0.007	0.746 ± 0.007	0.743 ± 0.007	0.746 ± 0.007	0.729 ± 0.007	0.743 ± 0.007
ψ-MAEg	41.5°	39.8°	39.8°	38.1°	38.3 ± 0.8 °	37.3 ± 0.8 °	36.8 ± 0.9°	36.1 ± 0.8°	38.2 ± 0.9°	36.6 ± 0.8°
ϕ-Q10d					54.6 ± 0.5%	55.6 ± 0.5%	54.8 ± 0.5%	56.1 ± 0.5%	54.9 ± 0.4%	56.1 ± 0.4%
ϕ-Q10%e					81.7 ± 0.4%	82.1 ± 0.4%	82.0 ± 0.4%	82.4 ± 0.4%	81.2 ± 0.4%	82.2 ± 0.3%
ϕ-PCCf					0.653 ± 0.005	0.658 ± 0.005	0.653 ± 0.005	0.659 ± 0.005	0.642 ± 0.006	0.654 ± 0.006
ϕ-MAEg					22.8 ± 0.4°	22.3 ± 0.4°	22.6 ± 0.3°	22.2 ± 0.4°	22.8 ± 0.4°	22.3 ± 0.3°
RSA-Q10d					39.0 ± 0.8%	39.7 ± 0.5%	39.2 ± 0.7%	39.9 ± 0.4%	38.7 ± 1.4%	39.7 ± 0.8%
RSA-Q10%e					57.0 ± 0.9%	58.0 ± 0.5%	57.4 ± 0.8%	58.1 ± 0.3%	56.5 ± 1.5%	57.7 ± 0.8%
RSA-PCCf					0.737 ± 0.004	0.744 ± 0.005	0.738 ± 0.004	0.745 ± 0.004	0.725 ± 0.005	0.742 ± 0.004
RSA-MAEg					0.114 ± 0.002	0.112 ± 0.001	0.113 ± 0.002	0.111 ± 0.001	0.117 ± 0.002	0.112 ± 0.001

^aThe number of proteins in the dataset, the number of hidden layers, and input window size.

^bNo guided weights.

^cGuided weights are used.

^dQ₁₀: Fraction of residues with correctly predicted states. Angles are divided into 10 states with 36° per bin.

^eQ_10%: Fraction of residues whose angles are predicted within 36° from the true value.

^fPearson’s correlation coefficient between predicted and actual values.

^gMean-absolute error between predicted and actual values. Degrees are used for the ϕ and ψ angles and [0, 1] normalization for the RSA.