Table 1.
LacZ mutant frequencies in spleens of RcsX tumor-bearing and control mice
Treatment | Animal code | No. of colonies (×105) | No. of mutants | Mutant frequency (×10−5) |
---|---|---|---|---|
Control | 303 | 5.60 | 67 | 12.0 |
305 | 1.28 | 7 | 5.5 | |
306 | 1.68 | 6 | 3.6 | |
307 | 6.00 | 54 | 9.0 | |
301 | 5.12 | 50 | 9.8 | |
304 | 2.62 | 20 | 7.6 | |
309 | 2.16 | 16 | 7.4 | |
310 | 9.80 | 70 | 7.1 | |
7.7 ± 2.6 | ||||
RcsX | 103 | 8.80 | 139 | 15.8 |
105 | 4.04 | 65 | 16.1 | |
106 | 2.72 | 25 | 9.2 | |
111 | 1.92 | 25 | 13.0 | |
104 | 3.56 | 43 | 12.1 | |
109 | 3.68 | 69 | 18.8 | |
101 | 4.86 | 123 | 25.3 | |
112 | 3.56 | 60 | 16.9 | |
15.9 ± 4.9 | ||||
RcsX + NMA | 203 | 8.52 | 99 | 11.6 |
207 | 10.56 | 106 | 10.0 | |
206 | 2.48 | 18 | 7.3 | |
204 | 12.08 | 84 | 6.9 | |
201 | 9.40 | 100 | 10.6 | |
208 | 6.48 | 82 | 12.7 | |
205 | 3.60 | 52 | 14.4 | |
210 | 6.72 | 66 | 9.8 | |
10.4 ± 2.5 | ||||
Control + NMA | 406 | 7.96 | 64 | 8.0 |
402 | 9.52 | 74 | 7.8 | |
401 | 2.40 | 13 | 5.4 | |
404 | 5.32 | 37 | 6.9 | |
403 | 4.08 | 36 | 8.8 | |
405 | 3.24 | 25 | 7.7 | |
407 | 2.16 | 24 | 11.1 | |
409 | 1.70 | 25 | 14.8 | |
8.8 ± 2.9 |