Table 3. Multivariable analysis of risk factors associated with non-adherence and default in a Tomsk TB treatment cohort.
| Outcome |
||||
|---|---|---|---|---|
| Non-adherence multivariate OR (95% CI) | Default multivariate OR (95% CI) | |||
| Male | 0.66 | 0.28–1.55 | 0.85 | 0.27–2.61 |
| Age > 40 | 0.84 | 0.37–1.90 | 1.98 | 0.65–6.08 |
| Unemployed | 1.15 | 0.49–2.69 | 2.62 | 0.76–9.06 |
| Previously incarcerated | 1.06 | 0.39–2.86 | 0.69 | 0.20–2.41 |
| Baseline alcoholism noted on initiation of treatment | 4.48 | 1.58–12.68 | 15.57 | 3.46–70.02 |
| Alcohol abuse first noted after initiation of treatmenta | 6.35 | 2.27–17.75 | 5.14 | 0.87–30.25 |
| Intravenous drug user at initiation of treatment | 16.64 | 3.24–85.56 | 2.58 | 0.21–30.96 |
| Any substance abuseb | 7.30 | 2.89–18.46 | 11.20 | 2.55–49.17 |
| Co-morbid conditions associated with side-effectsa | NIc | 7.20 | 1.94–26.75 | |
CI, confidence interval; OR, odds ratio. a Included in default model only. Other variables included in both models. b Included in model excluding alcoholism and drug use variables. c Not included.