Table 3.
Increased expression of NK cell related genes in peripheral blood from children with autism spectrum disorder compared with typically developing controls using microarray analysis.
| Fold-change | Gene Name | Protein Name |
|---|---|---|
| 2.2 | CCL4 | MIP-1 Beta |
| 1.7 | CCL5 | RANTES |
| 1.7 | CD160 | CD160 |
| 2.4 | CTSW | Cathepsin W/Lymphopain |
| 1.8 | CX3CR1 | Chemokine (CX3C motif) receptor 1 |
| 2.7 | GZMB | Granzyme B |
| 2.4 | GZMH | Granzyme H |
| 1.5 | GZMM | Granzyme M |
| 1.9 | IL2RB | Interleukin 2 receptor beta |
| 2.1 | ITGB2 | CD18/Beta 2 integrin |
| 1.5 | KIR2DL1 | KIR, two domains, long cytoplasmic tail |
| 1.7 | KIR2DL2 | |
| 1.5 | KIR2DL3 | |
| 1.6 | KIR2DL5A | |
| 2.2 | KIR2DS2 | KIR, two domains, short cytoplasmic tail |
| 1.7 | KIR2DS5 | |
| 1.7 | KIR3DL1 | KIR, three domains, long cytoplasmic tail |
| 1.7 | KIR3DL2 | |
| 1.7 | KIR3DL3 | |
| 1.8 | KLRD1 | CD94 |
| 1.7 | KLRF1 | ITIM2 |
| 2.5 | KSP37 | KSP37 protein |
| 1.5 | NFATC2 | Nuclear factor of activated T cells |
| 2.5 | NKG7 | Natural killer cell group 7, sequence |
| 1.9 | PDGFD | Platelet derived growth factor D |
| 2.6 | PRF1 | Perforin 1 |
| 2.2 | PTGDR | prostaglandin D2 receptor |
| 2.0 | TBX21 | T-box 21/TBET |
| 2.0 | TGFBR3 | Transforming growth factor β receptor III |
| 1.6 | TRGC2 | T cell receptor gamma constant 2 |