Table 4.
The top two annotation clusters identified by DAVID for up regulated probes in ASD. Count defines the number of genes occurring within specified group. False discovery rate (FDR) denotes the number of genes expected to occur within a group by chance.
| Enrichment Score: 5.96 | Count | p Value | FDR |
|---|---|---|---|
| Defense response | 22 | 1.20E-12 | 4.10E-09 |
| Immune response | 21 | 1.50E-12 | 2.50E-09 |
| Response to biotic stimulus | 22 | 3.00E-12 | 3.30E-09 |
| Cellular signaling | 28 | 8.20E-09 | 5.40E-06 |
| Disulfide bond formation | 27 | 9.10E-09 | 3.60E-05 |
| Signal peptide | 28 | 2.00E-07 | 4.00E-04 |
| Response to pest, pathogen or parasite | 13 | 4.90E-07 | 4.10E-04 |
| Response to other organism | 13 | 8.40E-07 | 5.70E-04 |
|
| |||
| Enrichment Score: 5.74 | Count | p Value | FDR |
|
| |||
| Natural killer cell mediated cytotoxicity | 13 | 9.70E-13 | 2.10E-10 |
| Antigen processing and presentation | 9 | 5.40E-09 | 5.80E-07 |
| Immunoglobulin subtype | 13 | 2.90E-08 | 1.50E-04 |
| Immunoglobulin-like | 13 | 1.10E-07 | 2.70E-04 |
| MHC class I receptor activity | 6 | 2.00E-07 | 1.60E-04 |