Table 5.
The top two annotation clusters identified by DAVID for down regulated probes in ASD. Count defines the number of genes occurring within specified group. False discovery rate (FDR) denotes the number of genes expected to occur within a group by chance.
| Enrichment Score: 7.49 | Count | p Value | FDR |
|---|---|---|---|
| Ribosome | 31 | 2.00E-13 | 6.40E-11 |
| Structural constituent of ribosome | 31 | 4.90E-13 | 1.20E-09 |
| Ribonucleoprotein complex | 40 | 1.00E-12 | 2.10E-10 |
| Protein biosynthesis | 44 | 2.80E-10 | 4.80E-07 |
| Macromolecule biosynthesis | 47 | 4.00E-10 | 4.60E-07 |
| Biosynthesis | 62 | 2.70E-08 | 2.30E-05 |
| Cellular biosynthesis | 57 | 4.40E-08 | 3.00E-05 |
| Large ribosomal subunit | 11 | 1.70E-07 | 1.50E-05 |
| Ribonucleoprotein | 22 | 3.00E-07 | 4.00E-04 |
| Ribosomal protein | 20 | 3.10E-07 | 2.00E-04 |
| Protein complex | 76 | 1.40E-05 | 9.00E-04 |
|
| |||
| Enrichment Score: 6.85 | Count | p Value | FDR |
|
| |||
| Intracellular processing | 250 | 2.10E-15 | 1.30E-12 |
| Cellular physiological process | 278 | 3.30E-12 | 1.10E-08 |
| Intracellular organelle | 215 | 5.30E-12 | 8.30E-10 |
| Cellular metabolism | 211 | 1.00E-07 | 5.90E-05 |
| Intracellular membrane-bound organelle | 179 | 3.90E-07 | 3.00E-05 |
| Membrane-bound organelle | 179 | 4.00E-07 | 2.80E-05 |
| Metabolism | 219 | 6.90E-07 | 3.30E-04 |
| Physiological process | 286 | 8.20E-07 | 3.50E-04 |