. Author manuscript; available in PMC: 2010 Jan 1.

Published in final edited form as: Brain Behav Immun. 2008 Aug 14;23(1):124–133. doi: 10.1016/j.bbi.2008.08.001

Table 6.

Frequency of CD56^Dim and CD56^Bright NK cell subsets that stain positively for perforin, granzyme B and IFNγ before and after stimulation. Frequency of cells ± standard error of mean (SEM) shown for each measure.

Assay	ASD	GP	P value
*Unstimulated, Perforin:*
CD56^Dim	43.8 ± 5.1 %	24.5 ± 7.1 %	0.0001
CD56^Bright	14.9 ± 2.3 %	11.3 ± 2.3 %	NS
*Stimulated, Perforin:*
CD56^Dim, 10:1 NK:K562	13.7 ± 2.5 %	47.0 ± 5.2 %	0.0001
CD56^Dim, 25:1 NK:K562	16.9 ± 3.4 %	53.4 ± 4.6 %	0.0001
CD56^Bright, 10:1 NK:K562	14.3 ± 2.0 %	26.7 ± 1.7 %	0.002
CD56^Bright, 25:1 NK:K562	12.6 ± 1.7 %	23.8 ± 3.6 %	0.005

*Unstimulated, Granzyme B:*
CD56^Dim	62.6 ± 4.9 %	47.5 ± 4.0 %	0.02
CD56^Bright	19.6 ± 1.8 %	17.1 ± 2.2 %	NS
*Stimulated, Granzyme B:*
CD56^Dim, 10:1 NK:K562	43.5 ± 2.4 %	67.6 ± 4.0 %	0.0001
CD56^Dim, 25:1 NK:K562	47.4 ± 4.7 %	74.6 ± 3.4 %	0.0001
CD56^Bright, 10:1 NK:K562	40.6 ± 5.4 %	68.8 ± 4.1 %	0.0004
CD56^Bright, 25:1 NK:K562	36.5 ± 3.9 %	71.7 ± 3.0 %	0.0001

*Unstimulated, IFNγ:*
CD56^Dim	39.1 ± 5.7 %	19.1 ± 3.9 %	0.003
CD56^Bright	72.1 ± 6.1 %	53.4 ± 6.1 %	0.04
*Stimulated, IFNγ:*
CD56^Dim, 0:1 NK:K562	21.2 ± 3.4 %	43.2 ± 4.1 %	0.0004
CD56^Dim, 25:1 NK:K562	30.6 ± 8.2 %	46.6 ± 4.4 %	NS
CD56^Bright, 10:1 NK:K562	52.1 ± 5.6 %	82.1 ± 4.8 %	0.0006
CD56^Bright, 25:1 NK:K562	56.4 ± 7.9 %	85.9 ± 5.0 %	0.009