. 2009 Jan;99(1):9–17. doi: 10.2105/AJPH.2007.128769

TABLE 1.

Drugs Approved by the US Food and Drug Administration With Academic Patents: 1988–2005

NDA No.	Tradename (Ingredient)	Approval Year	Public Sector Patent Holder
20 212	Zinecard (dexrazoxane hydrochloride)^a	1995	New York University
20 412	Zerit (stavudine)^a	1994	Yale University
20 413	Zerit (stavudine)	1996	Yale University
21 453	Zerit XR (stavudine)	2002	Yale University
20 819	Zemplar (paricalcitol)^b	1998	University of Wisconsin
21 606	Zemplar (paricalcitol)	2005	University of Wisconsin
21 636	Zegerid (omeprazole; sodium bicarbonate)	2004	University of Missouri
21 706	Zegerid (omeprazole; sodium bicarbonate)	2004	University of Missouri
20 597	Xalatan (latanoprost)^a	1996	Columbia University
20 961	Vitravene Preservative Free (fomivirsen sodium)^a	1998	US Government, HHS
20 569	Vitrasert (ganciclovir)	1996	University of Kentucky
21 119	Visudyne (verteporfin)^a	2000	Massachusetts General Hospital
20 154	Videx (didanosine)^a	1991	US Government, HHS
20 155	Videx (didanosine)	1991	US Government, HHS
20 156	Videx (didanosine)	1991	US Government, HHS
21 183	Videx ec (didanosine)	2000	US Government, HHS
21 267	Vfend (voriconazole)	2002	University of Kansas
21 602	Velcade (bortezomib)^a	2003	US Government, HHS
19 981	Ultratag (technetium TC-99M red blood cell kit)	1991	Associated Universities Inc.
21 752	Truvada (emtricitabine; tenofovir disoproxil fumarate)	2004	Emory University
20 408	Trusopt (dorzolamide hydrochloride)^a	1994	University of Florida
21 248	Trisenox (arsenic trioxide)^a	2000	Sloan-Kettering
20 505	Topamax (topiramate)^b	1996	New England Medical Center
20 844	Topamax Sprinkle (topiramate)	1998	New England Medical Center
20 898	Thyrogen (thyrotropin alfa)^a	1998	Sloan-Kettering
20 785	Thalomid (thalidomide)^a	1998	Children's Hospital Boston
20 262	Taxol (paclitaxel)^a	1992	US Government, HHS
21 055	Targretin (bexarotene)^a	1999	SRI International
19 836	Supprelin (histrelin acetate)^a	1991	Salk Institute
19 890	Stadol (butorphanol tartrate)	1991	University of Kentucky
20 657	Sporanox (itraconazole)	1997	US Government, HHS
21 106	Somavert (pegvisomant)^a	2003	Ohio University
19 608	Sildaflo (silver sulfadiazine)	1989	Research Corporation
21 544	Seasonale (ethinyl estradiol; levonorgestrel)	2003	Medical College of Hampton Roads
21 320	Plenaxis (abarelix)^a	2003	Indiana University
20 958	Pepcid Complete (calcium carbonate; famotidine; magnesium hydroxide)	2000	Brigham and Women's Hospital
19 880	Paraplatin (carboplatin)^a	1989	Research Corporation (on behalf of Michigan State University)
20 886	Panretin (alitretinoin)^a	1999	Salk Institute
19 927	Nizoral (ketoconazole)	1990	University of Tennessee
20 310	Nizoral A-D (ketoconazole)	1997	University of Tennessee
20 326	Neutrexin (trimetrexate glucuronate)^a	1993	US Government, HHS
21 487	Namenda (memantine hydrochloride)^b	2003	Children's Hospital Boston
20 586	Meretek UBT kit (with pranactin) (urea, C-13)^b	1996	Baylor College of Medicine
21 674	Menostar (estradiol)	2004	University of California
21 446	Lyrica (pregabalin)^a	2004	Northwestern University
20 845	Inomax (nitric oxide)^a	1999	Massachusetts General Hospital
20 199	Hivid (zalcitabine)^a	1992	US Government, HHS
20 076	Habitrol (nicotine)	1991	University of California
20 637	Gliadel (carmustine)	1996	Massachusetts Institute of Technology
19 863	Geref (sermorelin acetate)^b	1990	Salk Institute
20 443	Geref (sermorelin acetate)	1997	Salk Institute
21 481	Fuzeon (enfuvirtide)^a	2003	Duke University
20 038	Fludara (fludarabine phosphate)^a	1991	US Government, HHS
20 195	Fentanyl (fentanyl citrate)	1993	University of Utah
20 044	Exosurf neonatal (cetyl alcohol; colfosceril palmitate; tyloxapol)^a	1990	University of California
19 677	Enlon-plus (atropine sulfate; edrophonium chloride)	1991	University of California
21 500	Emtriva (emtricitabine)^b	2003	Emory University
21 896	Emtriva (emtricitabine)	2005	Emory University
20 193	Elmiron (pentosan polysulfate sodium)^b	1996	University of California
21 283	Diovan (valsartan)	2001	Brigham and Women's Hospital
20 869	Cosopt (dorzolamide hydrochloride; timolol maleate)	1998	University of Florida
21 673	Clolar (clofarabine)^a	2004	Southern Research Institute
21 197	Cetrotide (cetrorelix)^b	2000	Tulane University
19 829	Ceretec (technetium TC-99M exametazime kit)^a	1988	University of Missouri
19 785	Cardiolite (technetium TC-99M sestamibi kit)^b	1990	Harvard College
20 954	Busulfex (busulfan)	1999	University of Texas
20 404	Avita (tretinoin)	1997	University of California
21 316	Altoprev (lovastatin)	2002	Children's Hospital Boston
21 462	Alimta (pemetrexed disodium)^a	2004	Princeton University
19 937	Adenocard (adenosine)^a	1989	University of Virginia
20 747	Actiq (fentanyl citrate)	1998	University of Utah
20 162	Acthrel (corticorelin ovine triflutate)^a	1996	Salk Institute

Note. HHS = US Department of Health and Human Services; NDA = new drug application.

New molecular entity that received priority approval.

New molecular entities that did not receive priority approval.