Fig. 5.

Changes in side-chain positioning upon the binding of Zn²⁺ to Ca²⁺–S100B. (a) Residues on helix 4 (blue) and helix 1′ (red) of Ca²⁺–S100B prior to binding Zn²⁺. (b) Residues on helix 4 (blue) and helix 1′ (red) of Zn²⁺,Ca²⁺–S100B that changed in position upon binding Zn²⁺. (c) Average RMSDs for the position of side-chain atoms when the Ca²⁺–S100B and Zn²⁺,Ca²⁺–S100B structures are compared. Those residues with average RMSD values greater than 1 are labeled on the bar graph.