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. Author manuscript; available in PMC: 2009 Feb 5.
Published in final edited form as: Arthritis Rheum. 2008 Oct;58(10):3132–3144. doi: 10.1002/art.23946

Figure 2.

Figure 2

Osteoarthritis-like phenotype of knee joints from Col2a1–Smurf2 (Col2a1-Sf2)–transgenic mice. Knee joints were harvested, processed for histologic assessment, and 3-μm–thick sections were stained with Safranin O–fast green. Representative sections from Col2a1-Sf2 mice at ages 4.5 months (A), 6 months (B), and 8 months (C and D) are shown. Red arrows in C indicate areas of fibrillation and clefting in the cartilage. Black arrows in D indicate eburnation of subchondral bone. (Original magnification × 40.)