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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Mol Carcinog. 2008 Aug;47(8):608–615. doi: 10.1002/mc.20417

Table 2.

Concentrations of AFB1-DNA Adducts in Yeast DNA

Yeast genotype (strain)a AFB1-N7-Gua adducts/
mg DNA1b (nmol)		 FAPY adducts/mg
DNAc (nmol)		 Ratiod
Wild type (YB163) 4 × 10-3 1.1 × 10-3 4:1
rad53 (YB320) 4.5 × 10-3 2.3 × 10-3 2:1
a

Relevant genotype respect to RAD53, both strains derived from S288c. See Table 1 for complete genotype.

b

AFB1-N7 Gua, 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1; n = 2.

c

FAPY, formamidopyrimidine; FAPY determined for one sample of each genotype.

d

Ratio = major AFB1-N7-Gua adduct: FAPY adduct.