Table 2.
Significant Splicing Events
| Affymetrix Probeset ID | Gene and exon | LIMMA Comparison | Rank in analysis of unfiltered dataset (Benjamini-Hochberg-corrected p-value) | Rank with analysis of filtered dataset A (Benjamini-Hochberg-corrected p-value) | Rank with analysis of filtered dataset B (Benjamini-Hochberg-corrected p-value) |
| 3400083 | WNK1 exon 3 ENSE00000437674 |
Kidney vs. non-kidney | 53 (1.7e-12) |
11 (1.9e-12) |
1 (7.0e-12) |
| 3400090 | WNK1 exon 4 ENSE00000711974 |
Kidney vs. non-kidney | 82 (1.1e-11) |
21 (1.5e-11) |
4 (5.5e-11) |
| 3400056 | WNK1 exon 1 ENSE000001527902 |
Kidney vs. non-kidney | 161 (1.3e-10) |
44 (1.7e-10) |
9 (5.5e-10) |
| 3400080 | WNK1 exon 2 ENSE00000711927 |
Kidney vs. non-kidney | 507 (2.2e-08) |
169 (3.3e-08) |
35 (1.1e-07) |
| 3427830 | SLC25A3 exon3B ENSE00000753648 |
Muscle vs. non-muscle | 25 (5.9e-13) |
3 (1.3e-12) |
2 (1.2e-12) |
| 3427830 | SLC25A3 exon3B ENSE00000753648 |
Heart vs. non-heart | 106 (1.7e-11) |
41 (1.1e-11) |
8 (3.6e-11) |
| 3427827 | SLC25A3 exon 3A ENSE00000753647 |
Heart vs. non-heart | 236 (5.2e-10) |
112 (5.8e-10) |
26 (1,8e-09) |
| 3427827 | SLC25A3 exon 3A ENSE00000753647 |
Muscle vs. non-muscle | 263 (1.6e-09) |
126 (1.7e-09) |
35 (4.6e-09) |
| 3427827 | SLC25A3 exon 3A ENSE00000753647 |
Thyroid vs. non-thyroid | 308 (3.9e-07) |
114 (1.2e-09) |
22 (2.2e-06) |
| 3918911 | ITSN exon 40 ENSE00001488185 |
Cereb. vs. non-cereb | 480 (1.6e-12) |
225 (1.7e-12) |
63 (4.4e-12) |
| 3918909 | ITSN exon 40 ENSE00001488185 |
Cereb. vs. non-cereb | 1822 (1.7e-09) |
873 (2.0e-09) |
353 (3.6e-09) |
| 3918908 | ITSN exon 40 ENSE00001488185 |
Cereb. vs. non-cereb | 1884 (2.1e-09) |
885 (2.1e-09) |
359 (3.8e-09) |
| 3918903 | ITSN exon 35 ENSE00001488224 |
Cereb. vs. non-cereb | 2304 (6.6e-09) |
1107 (7.2e-09) |
466 (1.2e-08) |
| 2562711 | IMMT exon 6 ENSE00000768006 |
Heart vs. non-heart | 37 (4.5e-13) |
17 (3.7e-13) |
1 (4.3e-12) |
| 2319719 | KIF1B exon 20 ENSE00001472763 |
Heart vs. non-heart | 129 (3.6e-11) |
55 (3.1e-11) |
Not present in dataset B |
| 2319721 | KIF1B exon 20 ENSE00001472763 |
Heart vs. non-heart | 134 (4.4e-11) |
61 (4.2e-11) |
Not present in dataset B |
| 2319722 | KIF1B exon 20 ENSE00001472763 |
Cereb. vs. non-cereb | 486 (1.8e-12) |
218 (1.7e-12) |
Not present in dataset B |
| 2319721 | KIF1B exon 20 ENSE00001472763 |
Cereb. vs. non-cereb | 1784 (1.4e-09) |
830 (1.4e-09) |
Not present in dataset B |
Table showing the effect of filtering on the ranking of real splice events. All the probesets in the table had a Benjamini-Hochberg-corrected p-value less than 0.0001 and for each there is literature evidence of the identified splicing events.