Table 2. Top 15 significant gene ontology categories determined by EASE analysis for B-Myb associated genes.

Significant genes, as determined by SAM, for doxorubicin-treated B-Myb overexpressing HME-CC cells versus doxorubicin-treated controls were input to EASE and analyzed for enriched gene ontology categories.

Doxorubicin-induced genes:
Gene Ontology Category	List Hits	List Total	Population Hits	Population Total	Bonferroni p-value
Mitotic cell cycle	58	138	352	13248	2.59E-51
Cell cycle	65	138	745	13248	8.60E-41
M phase	37	138	174	13248	1.22E-34
Nuclear division	35	138	167	13248	2.84E-32
Mitosis	32	138	131	13248	2.31 E-31
M phase of mitotic cell cycle	32	138	133	13248	3.87E-31
Cell proliferation	65	138	1116	13248	4.33E-30
DNA replication and chromosome cycle	29	138	199	13248	2.21 E-21
DNA metabolism	36	138	579	13248	4.60E-15
DNA replication	20	138	156	13248	1.22E-12
S phase of mitotic cell cycle	20	138	158	13248	1.54E-12
Spindle	17	135	97	12954	1.66E-12
Regulation of cell cycle	28	138	406	13248	4.68E-12
Cytokinesis	16	138	112	13248	3.14E-10
Cell growth and/or maintenance	81	138	3996	13248	3.44E-09