Table 2.
Evaluation of immunohistochemical parameters
| rAAV1-GFP | rAAV1-K1K3 | |
|---|---|---|
| ED-1 | ||
| TI | 1,005±194 | 625±73* |
| G | 32±5 | 19±3* |
| CD4 | ||
| TI | 1,720±470 | 1,526±427 |
| G | 27±6 | 15±2* |
| CD8 | ||
| TI | 621±110 | 513±68 |
| G | 9±2 | 5±2* |
| OX62 | ||
| TI | 552±93 | 341±58* |
| Collagen I | ||
| TI | 23,380±2,232 | 14,735±1,799* |
| JG-12 | ||
| TI | 16,430±1,219 | 13,857±1,367* |
Data are expressed as mean positive pixels per field ± SD; n = 6. TI, tubulointerstitial; G, glomerular; rAAV, recombinant adeno-associated virus; GFP, green fluorescence protein.
*
P < 0.05 vs. rAAV1-GFP rats.