Table 3.
mRNA expression in rat kidney
| rAAV1-GFP | rAAV1-K1K3 | |||
|---|---|---|---|---|
| Adhesion molecules | ||||
| ICAM-1 | 0.124±0.045 | 0.106±0.016 | ||
| VCAM-1 | 0.018±0.005 | 0.014±0.004 | ||
| E-selectin | 0.031±0.014 | 0.015±0.003 | ||
| P-selectin | 0.079±0.033 | 0.022±0.011 | ||
| Extracellular matrix molecules | ||||
| Collagen IVα5 | 0.047±0.007 | 0.032±0.003* | ||
| TGF-β | 0.022±0.01 | 0.011±0.002 | ||
| Angiogenesis molecules | ||||
| VEGF-A | 0.090±0.009 | 0.087±0.009 | ||
| VEGF-C | 0.007±0.002 | 0.006±0.001 | ||
| VEGFR1 (Flt-1) | 0.011±0.001 | 0.007±0.001* | ||
| VEGFR2 (KDR) | 0.020±0.003 | 0.017±0.002 | ||
| Angiopoietin-1 | 0.017±0.003 | 0.019±0.004 | ||
| Angiopoietin-2 | 0.008±0.002 | 0.005±0.002 | ||
| Tie-2 | 0.005±0.001 | 0.003±0.001* | ||
| Cytokines and chemokine | ||||
| MCP-1 | 0.046±0.01 | 0.027±0.002* | ||
| IL-2 | 0.022±0.006 | 0.023±0.009 | ||
| INF γ | 0.031±0.007 | 0.028±0.01 | ||
Data are expressed as mean gene expression/GAPDH ratio ± SD; n = 6.
P < 0.05 vs. rAAV1-GFP rats.