Table 3.
rAAV1-GFP | rAAV1-K1K3 | |||
---|---|---|---|---|
Adhesion molecules | ||||
ICAM-1 | 0.124±0.045 | 0.106±0.016 | ||
VCAM-1 | 0.018±0.005 | 0.014±0.004 | ||
E-selectin | 0.031±0.014 | 0.015±0.003 | ||
P-selectin | 0.079±0.033 | 0.022±0.011 | ||
Extracellular matrix molecules | ||||
Collagen IVα5 | 0.047±0.007 | 0.032±0.003* | ||
TGF-β | 0.022±0.01 | 0.011±0.002 | ||
Angiogenesis molecules | ||||
VEGF-A | 0.090±0.009 | 0.087±0.009 | ||
VEGF-C | 0.007±0.002 | 0.006±0.001 | ||
VEGFR1 (Flt-1) | 0.011±0.001 | 0.007±0.001* | ||
VEGFR2 (KDR) | 0.020±0.003 | 0.017±0.002 | ||
Angiopoietin-1 | 0.017±0.003 | 0.019±0.004 | ||
Angiopoietin-2 | 0.008±0.002 | 0.005±0.002 | ||
Tie-2 | 0.005±0.001 | 0.003±0.001* | ||
Cytokines and chemokine | ||||
MCP-1 | 0.046±0.01 | 0.027±0.002* | ||
IL-2 | 0.022±0.006 | 0.023±0.009 | ||
INF γ | 0.031±0.007 | 0.028±0.01 |
Data are expressed as mean gene expression/GAPDH ratio ± SD; n = 6.
P < 0.05 vs. rAAV1-GFP rats.