Fig. 9.
Endothelial [Ca2+]CYT response to bradykinin (BK) is reduced in DVR from OH rats. A: tracings show means ± SE of [Ca2+]CYT responses of fura2-loaded DVR to BK (100 nmol/l) exposure. Vessels were obtained from vehicle (n = 8)- or ouabain-treated rats (n = 9, OH rat). Ouabain treatment reduced the [Ca2+]CYT response to BK. *P < 0.05 OH rat DVR vs. control for all times > 4.5 min. B: summary of means ± SE of integrated AUC responses for vessels in A. *P < 0.05 OH rat DVR vs. vehicle, n = 8, 10, respectively.