Effect of LBP antibody blockade on Kupffer cell production of IL-6, MIP-2, and IL-1ra following LPS stimulation. LBP antibody blockade significantly reduces C57BL/6 Kupffer cell production of IL-6 (A), MIP-2 (B), and IL-1ra (C) following stimulation of cells with LPS (100 ng/ml), *P < 0.001 compared with 0-μg LBP antibody dose.