Table 1.
Effects of IES on AUC of contractions after a solid meal during baseline, treatment, IES, and recovery in the antropyloroduodenal region
|
AUC, mmHg/s |
||||
|---|---|---|---|---|
| Baseline | Treatment | IES | Recovery | |
| Antrum | ||||
| Control | 6.7±3.4 | 6.8±2.9 | 4.8±2.3 | 5.4±2.7 |
| l-NNA iv | 10.9±5.8 | 11.9±5.4 | 5.5±1.0 | 11.4±11.7 |
| Phentolamine | 10.1±3.8 | 12.3±1.6 | 12.2±1.5 | 10.3±3.1 |
| Pylorus | ||||
| Control | 7.1±4.2 | 11.31±6.4 | 4.7±3.7 | 11.3±8.7 |
| l-NNA iv | 10.5±5.0 | 32.3±3.5† | 4.0±2.0* | 33.6±15.0† |
Values (means ± SD) are expressed as area under the curve (AUC) during 4 consecutive 20-min periods [baseline, treatment, intestinal electrical stimulation (IES), and recovery]. Saline (control) or N-nitro-l-arginine (l-NNA) was administered during treatment period.
*
P < 0.05 vs. treatment or recovery.
†
P < 0.05 vs. control.