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Recombinant apo AIV on food intake. Fasted rats (n = 5 or 6) received a bolus dose either via intraperitoneal or intravenous route, 0.25 ml of either saline alone or one dose of recombinant apo AIV (100, 200, or 500 μg/kg) in 0.9% saline 5 min before refeeding. Food intake was measured at 30 (A), 60 (B), and 120 (C) min. Data are presented as means ± SE. a,b,c,dDiffering letters indicate significance of P < 0.05 compared with the control group at same time point.
