Table 3.
Parameter | Interpretation | FVB | PyMT | HER2 | DMBA | |||||
---|---|---|---|---|---|---|---|---|---|---|
Prepubertal phase | ||||||||||
a1 | Weight at maximum growth rate, g | 12.1 (0.12)a | 12.0 (0.18)b | 13.5 (1.6)a,b | 10.7 (0.45)c | |||||
a1 × b1 | Maximum growth rate, g/PND | 0.681 (0.03)b | 0.721 (0.02)a | 0.761 (0.07)a | 0.729 (0.02)a | |||||
d1 | Age at maximum growth rate, PND | 21.3 (0.43)a | 17.6 (0.41)b | 20.5 (1.3)a | 16.7 (0.29)b | |||||
Postpubertal phase | ||||||||||
2a1 + a2 | Weight at maximum growth rate, g | 44.8 (23.9)a | 31.5 (0.5)a | |||||||
a2 × b2 | Maximum growth rate, g/PND | 0.0947 (0.07)a | 0.116 (0.01)a | |||||||
d2 | Age at maximum growth rate, PND | 332.7 (233.7)a | 154.2 (5.8)a |
Values are means (±SE), with significant differences between breast cancer models that do not share a letter a, b, or c (P < 0.05). Parameters were estimated from monophasic and diphasic sigmoidal curves (27).