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Downregulation of CD74 prevents MIF actions on podocytes. siRNA downregulation of CD74 protein (Western blot; A) prevents ERK1/2 (B) and p38 (C) phosphorylation induced by 50 ng/ml MIF for 30 min. Data are means ± SD of three independent experiments. (B) *P < 0.05 versus control; **P < 0.01 versus MIF alone. (C) *P < 0.05 versus control; **P < 0.01 versus MIF alone.
