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Mice were killed 8 wk after BM transplantation, and renal tissue was examined. (A) The extent of glomerular crescents and necrosis was expressed as the mean percentage of glomeruli with crescents and necrosis. (B) Glomerulus from a C5aR−/− mouse with no lesion.(C through E) WT mice developed glomerular crescents and necrosis. (F and G) Examination for glomerular neutrophil infiltration showed that C5aR−/− mice had fewer glomerular neutrophils (F) than did WT mice (G). **P < 0.01.
