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. 2009 Feb;20(2):289–298. doi: 10.1681/ASN.2008050497

Table 1.

Pathologic findings in MPO-deficient micea

Group Mice with Crescents (% [n]) % Glomeruli with Crescents per Mouse
% Glomeruli with Necrosis per Mouse (Mean ± SEM)
% Engraftment with MPO-Positive PMN (Mean ± SEM)
Mean ± SEM Range (%) Mean ± SEM Range (%) Mean ± SEM Range (%)
WT 100 (6/6)b 11.3 ± 3.4b 5.4 to 24.1 6.1 ± 1.8b 3.2 to 14.5 91.3 ± 3.2 80 to 100
C5aR−/− 12.5 (1/8) 0.5 ± 0.3 0.0 to 2.1 0.0 ± 0.0 91.5 ± 6.3 82 to 100
a

Mice received WT or C5aR−/− BM.

b

P < 0.01.

HHS Vulnerability Disclosure