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. Author manuscript; available in PMC: 2009 Feb 6.
Published in final edited form as: Circulation. 2008 Feb 19;117(10):1255–1260. doi: 10.1161/CIRCULATIONAHA.107.744466

Table 4.

Metabolic Syndrome and Risk of AF: Multivariable Models*

Variables HR (95% CI) P
Metabolic syndrome
  NCEP-ATPIII
    All subjects 1.88 (1.40–2.52) <0.001
    Subjects without treated hypertension or diabetes> 1.78 (1.07–2.96) 0.03
  AHA/NHLBI
    All subjects 1.61 (1.21–2.15) 0.001
    Subjects without treated hypertension or diabetes 1.28 (0.78–2.1) 0.33
Metabolic syndrome components
  Obesity 1.64 (1.26–2.15) <.001
  Elevated blood pressure 1.69 (1.26–2.27) <0.001
  Low HDL cholesterol 1.52 (1.09–2.14) 0.01
  Elevated triglycerides 1.13 (0.81–1.57) 0.47
  Impaired glucose tolerance (NCEP-ATPIII) 1.44 (1.09–1.90) 0.01
  Impaired glucose tolerance (AHA/NHLBI) 1.35 (1.06–1.73) 0.01
Metabolic syndrome components, n
  NCEP-ATPIII
    0 1.00
    1 1.95 (1.30–2.93) 0.001
    2 2.05 (1.34–3.15) 0.001
    ≥3 3.27 (2.10–5.10) <0.001
    Trend across number of components 1.38 (1.21–1.56) <0.001
  AHA/NHLBI
    0 1.00
    1 2.33 (1.47–3.72) <0.001
    2 2.54 (1.59–4.07) <0.001
    ≥3 3.39 (2.08–5.53) <0.001
    Trend across number of components 1.35 (1.19–1.53) <0.001

HR indicates hazard ratio.

*

Models were adjusted for age and gender.

Probability value was calculated from a test for trend in 4 groups based on number of fulfilled components.