Figure 1.
Family of receiver operating characteristic (ROC) curves and area under the ROC curve (AUROC) values of a surrogate marker vs. true disease used in the estimation of the validity (AUROC) of the surrogate marker vs. the liver biopsy. These AUROC values represent the full range of sensitivity and specificity of a surrogate marker vs. true disease at an infinte number of cut-offs for defining true disease.