Figure 4.

ARCaP tumor growth in sham-operated and castrated male hosts under various hormonal conditions. ARCaP cells were injected subcutaneously into sham-operated or castrated male athymic mice [treated every other day with 50 μl of corn oil, 200 μg of testosterone propionate (TP)/50 μl of corn oil, or 50 μg of estradiol dipropionate (E₂P₂)/50 μl of corn oil]. Note tumor growth is faster in castrated than in intact hosts, and the growth of ARCaP tumors in castrated hosts is depressed by the administration of either TP or E₂P₂ alone. Data are expressed as average tumor volume ± SEM of six determinations.