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. Author manuscript; available in PMC: 2009 Feb 6.
Published in final edited form as: J Ocul Pharmacol Ther. 2008 Feb;24(1):104–115. doi: 10.1089/jop.2007.0074

Table 1.

Ocular and systemic penetration of 3H WIN 55212-2 after a single topical dose (20 µL)

3H WIN 55212-2 (µM)

60 min 120 min N/group
Cornea 84.7 ± 25.0 117.0 ± 19.7 4
Vitreous humor 76.6 ± 26.7 47.4 ± 12.5 4
Retina/sclera 95.7 ± 12.9 66.3 ± 15.4 4
Eyelids 1169.9 ± 482.8 1154.4 ± 792.8 4
Blood BDL BDL 2
Liver BDL 0.1 ± 0.0 2
Urine 0.2 ± 0.1 2.2 ± 0.7 2

BDL, below detection limit.