Table 3.
Progression (Regression) of Atherosclerosis Over a 2.5-Year Period (in the Placebo Group) According to the Genotypes of rs2383206 SNP at the 9p21 Locus
| Genotypes | ||||
| GG | GA | AA | P | |
| N = 141 | 32 | 78 | 31 | |
| New coronary lesion (mean) | 0.34 ± 0.48 | 0.38 ± 0.49 | 0.26 ± 0.45 | 0.462 |
| Subjects with new coronary lesions (%) | 11 (34.3) | 30 (38.4) | 8 (25.8) | 0.265 |
| New coronary occlusions (mean) | 0.03 ± 0.18 | 0.08 ± 0.27 | 0.06 ± 0.25 | 0.678 |
| Subjects with new coronary occlusions (%) | 1 (3.1) | 6 (7.7) | 2 (6.5) | 0.209 |
| Average final MLD (mm) | 1.54 ± 0.40 | 1.62 ± 0.41 | 1.59 ± 0.39 | 0.657 |
| Change in MLD (mm) | -0.09 ± 0.25 | -0.11 ± 0.23 | -0.11 ± 0.25 | 0.928 |
Abbreviations: m: meter; Kg: Kilogram; mmHg: millimeter mercury; mg/dl: milligram per deciliter; HDL-C: High-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol; Apo A: apolipoprotein A; Apo B: apolipoprotein B; Apo C-III: apolipoprotein C3; MLD: minimal lumen diameter.