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The effect of low and high concentrations of CORT in KA-induced apoptosis. Cortical neurons (10–12DIV) were treated with CORT (100 nM, 1 μM) for 1 day in Neurobasal and 3 days in N2 plus Neurobasal. KA (50 μM) was then applied for 12 h to challenge the neurons. Neuronal apoptosis was determined by TUNEL assay (n = 2, n = 17–29 for each group. One-way ANOVA, *P < 0.05, **P < 0.01). Data are presented as mean ± SE.
