Table 1.

Thermodynamic properties of cyclic peptide complexes of [Co^III(coproporphyrinate I)]^3-

Parameter	Cy-AA-KK	Cy-AA-EK	Cy-FF-KK
Tm, °C*	47 ± 3	47 ± 3	52 ± 3
ΔSm, cal·mol-1·deg-1†	31 ± 5	47 ± 5	34 ± 5
ΔHm, kcal·mol-1‡	9.9 ± 2	15.0 ± 2	11.1 ± 3
ΔG°unfolding, kcal·mol-1§	2.9 ± 0.24	3.3 ± 0.26	—¶
m, cal·mol-1·M-1∥	598 ± 47	735 ± 54	—¶

^*Melting temperature. This is the temperature when ΔG = 0 and the molecule is half-unfolded

^†Entropy of unfolding (1 cal = 4.184 J)

^‡van't Hoff enthalpy

^§Free energy of unfolding in urea

^¶Not measured because of the dynamic nature of the complex and limited sample quantities

^∥Molar cosolvation term