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. Author manuscript; available in PMC: 2009 Feb 7.
Published in final edited form as: Genesis. 2008 Aug;46(8):431–439. doi: 10.1002/dvg.20418

Figure 5. TAB1 is involving in BMP signaling cascade.

Figure 5

A. Expression analysis of Id1 in Tab1 mutants at E16.5. Id1 expression levels were downregulated in mesenchymal regions of intestine in Tab1 mutant embryos.

B. Wild type and Tab1-deficient (−/−) MEFs were cultured with BMP4 and Id1 expression was determined by RT-PCR. An increase in Id1 expression levels was observed in BMP4-treated control MEFs, however there was no induction of Id1 expression in Tab1-deficient (−/−) MEFs after stimulated by BMP4. β-actin was used as an internal control.